 
 
	CD191抗体经ICC, IHC, WB, FACS严格验证,品质保证.广泛种属反应性附有用户反馈信息.确保特异性!**的技术支持帮您更快得到实验结果,现货.我司提供8万种科研用专业抗体,经严格质控,特异性高,可重复性强,验证数..可与小鼠, 大鼠, 人样本反应并经WB, IHC, ICC实验严格验证。所有产品均提供质保服务,中国75%以上现货。
	产品编号bs-1169R
	
		英文名称CCR-1/CD191
	
	
		中文名称细胞表面趋化因子受体1抗体
	
	
		别    名CC chemokine receptor 1; A630091E18Rik; CC-CKR-11; CCBP2; CCR10; CCR11; CCRL1; CCX-CKR; CCX-CKR1; CKR-11; Cmkbrl1; LOC684092; LOC685243; PPR1; VSHK1; C C chemokine receptor type 1; C C CKR 1; CC CKR 1; CCR 1; CD 191; CD191; CD191; Chemokine (C-C motif) receptor 1; Chemokine C C motif receptor 1; CKR 1; CKR1; CMKBR 1; CMKBR1; CMKR 1; CMKR1; HM145; LD78 receptor; Macrophage inflammatory protein 1 alpha /Rantes receptor; Macrophage inflammatory protein 1 alpha receptor; MIP 1alpha R; Mip-1a-R; MIP1aR; RANTES R; RANTES receptor; SCYAR1; CCR1_HUMAN; C-C chemokine receptor type 1; C-C CKR-1; CC-CKR-1; Short=CCR-1; CCR1; LD78 receptor; MIP-1alpha-R; RANTES-R; CD191.  
	
	
		规格价格50ul/780元 购买    100ul/1280元 购买    200ul/1980元 购买    大包装/询价
	
	
		说 明 书50ul  100ul  200ul
	
	
		研究领域细胞生物  **学  
	
	
		抗体来源Rabbit
	
	
		克隆类型Polyclonal
	
	
		交叉反应 Human, Mouse, Rat,
	
	
		CD191抗体产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
	
	
		not yet tested in other applications.
	
	分 子 量177kDa
	细胞定位细胞浆 
	性    状Lyophilized or Liquid
	浓    度1mg/1ml
	免 疫 原KLH conjugated synthetic peptide derived from human Nestin
	亚    型IgG
	纯化方法affinity purified by Protein A
	储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
	保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
	PubMedPubMed
	CD191抗体产品介绍background:
	Nestin is a Class VI intermediate filament expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells. This protein has been widely used as a predominant marker for stem / progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS. Furthermore, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumor.
	Function:
	Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
	Subunit:
	Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, this protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3.
	Subcellular Location:
	Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, tis protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3
	Tissue Specificity:
	CNS stem cells.
	Post-translational modifications:
	Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
	Similarity:
	Belongs to the intermediate filament family.
	SWISS:
	P48681 
	Gene ID:
	10763
	Database links:
	CD191抗体溶解方法:
	1、在我们公司购买抗体后,查看标签上的规格,如:0.1ml、0.2ml 
	2、 以规格为0.1ml的冻干粉抗体为例(部分抗体为液体,无需再溶解): 
	溶解方法一:用移液器加0.1ml双蒸水到试管内,混匀,-20℃保存; 
	若为其它规格(如:0.2ml)的冻干粉抗体,则加与标签上规格一致的(如:0.2ml)双蒸水溶解,混匀,-20℃保存。 
	溶解方法二:用移液器加 0.05ml(规格的 50%)双蒸水到试管内,再加 0.05ml(规格的 50%)
	的甘油到试管内,混匀,-20℃保存; 若为其它规格(如:0.2ml)的冻干粉抗体,则加标签上规格的 50%(如:0.1ml)双蒸水,再加标签上规格的50%(如:0.1ml)甘油溶解,混匀,-20℃保存。 
	3、抗体的分装 
	抗体溶解后,将其分装成 5-10支(以0.1mlCD191抗体为例,20ulx5支或 10ulx10支),-20℃保存,用一支取一支,避免反复冻溶。 
	另:预试验可做几个梯度1:100、1:200、1:400稀释,如果背景高,还可再稀释,选一个*佳的稀释比例,再正式做,效果*好。工作液可用“抗体稀释液”稀释。
	后续试验时,再使用对应的缓冲液稀释成工作液,即用即配。
	我们的抗体(冻干粉),在常温放置下,至少一个月有效;若在-20℃下保存(推荐),至少三年有效。
	CD191抗体关联产品列表:
bs-5365R	No			合格	phospho-HSP70 (Tyr525) 	磷酸化热休克蛋白70抗体
bs-5367R	No	合格			phospho-GSK-3 Beta(Ser21+Ser29)	磷酸化糖原合酶激酶3β抗体
bs-5368R	No	合格			phospho-GSK-3 Beta(Ser21)	磷酸化糖原合酶激酶3β抗体
bs-5376R	YES		合格		phospho-G3BP1(Ser232)	磷酸化Ras GTP酶活化蛋白结合蛋白1抗体
bs-5381R	No	合格			Phospho-NMDAR2B (Tyr1336)	磷酸化谷氨酸受体2B抗体
bs-5388R	No	合格			phospho-HDAC1 (Ser423+Ser421) 	磷酸化组蛋白去乙酰化酶1抗体
bs-5390R	No	合格			Seladin 1	24脱氢胆固醇还原酶抗体
bs-5392R	No		合格		phospho-HOMER3 (Thr36)	磷酸化HOMER3蛋白抗体
bs-5393R	No		合格		phospho-IKK gamma(Ser43)	磷酸化KB抑制蛋白激酶γ抗体
bs-5394R	No			合格	phospho-IL-1R1(Tyr496)	磷酸化白介素1受体1抗体
bs-5395R	No	合格			phospho-IL-7Ra (Tyr449)	磷酸化白细胞介素-7受体a抗体
bs-5396R	YES			合格	phospho-IRS1 (Ser312)	磷酸化胰岛素受体底物-1抗体