Recombinant Human AITR Ligand/TNFSF18
产品编号
产品名称
产品包装
产品价格
XY435-1mg
1mg
26773.00元
Species
Gene ID
Accession
Source
Length
MW
Tag
Human
8995
Q9UNG2
E. coli
126aa
14.3kDa
－
About this Antibody
Name
Recombinant Human AITR Ligand/TNFSF18 (Recombinant Human Activation-induced TNFR member Ligand/TNFSF18; rHuAITR Ligand/TNFSF18)；重组人诱导激活TNFR成员配体/TNFSF18
Synonyms
TNFSF18; Activation-inducible TNF-related ligand; AITRLMGC138237; GITRLglucocorticoid-induced TNFR-related protein ligand; Glucocorticoid-induced TNF-related ligand; hGITRLGITR ligand; TL6AITR ligand; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18
Purity
>98% by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The biological activity as determined by stimulation of IL-8 production using human PBMC is in a concentration range of 0.1-10ng/ml.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.
Endotoxin
Less than 0.1EU/μg of rHuAITR Ligand/TNFSF18 as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
Category
Cytokine
Background
TNFSF18, also named as AITRL, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family and it is encoded by the TNFSF18 gene. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. It is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 is a 14.3kDa protein, containing 126 amino acid residues and it shares 56% and 60%a.a. sequence identity with murine and rat TNFSF18, respectively.
Amino Acid Sequence
ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFIS
包装清单:
包装
XY435-5μg
5μg
XY435-20μg
20μg
XY435-100μg
100μg
-
说明书
1份
保存条件: -20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。 注意事项: 由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。 本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。 为了您的**和健康，请穿实验服并戴一次性手套操作。