核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体
规格：1mg/1ml
英文名： Nucleostemin
别名： E2 induced gene 3 protein; E2IG3; Estradiol induced nucleotide binding protein; GNL3; Guanine nucleotide binding protein like 3 (nucleolar); Guanine nucleotide binding protein like 3; MGC800; NNP47; N
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Nucleost
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞核
核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体产品介绍：background: Nucleostemin is a protein found in the nucleoli of embryonic stem cells, ***** CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most ***** tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells. Function: May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis. Subunit: Interacts with MDM2; this interaction stabilizes MDM2. Interaction with MDM2 occurs in the nucleoplasm and is triggered by a nucleolar release mechanism, such as mitosis-induced nucleolar disassembly (By similarity). Indirectly interacts with TP53, via MDM2-binding (By similarity). Subcellular Location: Nucleus. Nucleus. nucleolus. 核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体Shuttles between the nucleus and nucleolus. Tissue Specificity: Increased levels in lung tissue in cancer patients. Similarity: Belongs to the MMR1/HSR1 GTP-binding protein family. Contains 1 G (guanine nucleotide-binding) domain. Gene ID:核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体 26354 Database links: Entrez Gene: 26354 Human Entrez Gene: 30877 Mouse Entrez Gene: 290556 Rat Omim: 608011 Human SwissProt: Q9BVP2 Human SwissProt: Q8CI11 Mouse SwissProt: Q811S9 Rat Unigene: 313544 Human Unigene: 88512 Mouse Unigene: 4110 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 干细胞 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid