细胞毒颗粒相关蛋白TIA-1抗体
规格：1mg/1ml
英文名： TIA1
别名： Cytotoxic granule associated RNA binding protein 1; Cytotoxic granule associated RNA binding protein; mTIA-1; Nucleolysin TIA 1 isoform p40; Nucleolysin TIA-1 isoform p40; Nucleolysin TIA1 isoform p40
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TIA1
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位：细胞核 细胞浆
细胞毒颗粒相关蛋白TIA-1抗体产品介绍：background: Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. Function: Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic细胞毒颗粒相关蛋白TIA-1抗体 lymphocyte target cells. May be involved in apoptosis. Subcellular Location: Cytoplasmic granule. Nucleus. Note=Accumulates in cytoplasmic stress granules (SG) following cellular damage. Similarity: Contains 3 RRM (RNA recognition motif) domains. Gene ID: 7072 Database links: Entrez Gene: 7072 Human Entrez Gene: 21841 Mouse Entrez Gene: 312510 Rat Omim: 603518 Human SwissProt: P31483 细胞毒颗粒相关蛋白TIA-1抗体Human SwissProt: P52912 Mouse Unigene: 413123 Human Unigene: 333219 Mouse Unigene: 198158 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产细胞毒颗粒相关蛋白TIA-1抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 染色质和核信号 信号转导 细胞凋亡 表观遗传学
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid