脱氧核糖核酸酶2抗体
规格:1mg/1ml
英文名: DNase II
别名: Acid DNase; Deoxyribonuclease 2 alpha; Deoxyribonuclease 2; Deoxyribonuclease II alpha; Deoxyribonuclease II; Deoxyribonuclease II lysosomal; Deoxyribonuclease-2-alpha; Deoxyribonuclease2; Deoxyribonu
分子量: 38kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DNase II
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位:细胞浆
产脱氧核糖核酸酶2抗体品介绍:background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. Function: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis脱氧核糖核酸酶2抗体 during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. Subcellular Location: Lysosome. Post-translational modifications: Glycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect. Similarity: Belongs to the DNase II family. Gene ID:脱氧核糖核酸酶2抗体 1777 Database links: Entrez Gene: 1777 Human Omim: 126350 Human SwissProt: O00115 Human Unigene: 118243 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脱氧核糖核酸酶2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 细胞凋亡 细胞周期蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid