三磷酸腺苷门控阳离子通道蛋白抗体
规格：1mg/1ml
英文名： P2RX4
别名： ATP gated cation channel protein; ATP receptor; p2rx4; P2RX4_HUMAN; P2X purinoceptor 4; P2X receptor subunit 4; P2X4; P2X4R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 4; Pu
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human P2RX4
交叉反应：Human, Mouse, Rat, Dog, Cow,
细胞定位：细胞膜
三磷酸腺苷门控阳离子通道蛋白抗体产品介绍：background: The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations 三磷酸腺苷门控阳离子通道蛋白抗体of extracellular ATP. Function: Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. Subunit: Functional P2XRs are organized as homomeric and heteromeric trimers. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the P2X receptor family. Gene ID: 5025 Database links: Entrez Gene: 338036 Cow Entrez Gene: 448783 Dog Entrez Gene: 5025 Human Entrez Gene: 18438 Mouse Entrez Gene: 100458831 Orangutan Entrez Gene: 29659 Rat Omim: 600846 三磷酸腺苷门控阳离子通道蛋白抗体Human SwissProt: Q5E9U1 Cow SwissProt: Q99571 Human SwissProt: Q9JJX6 Mouse SwissProt: P51577 Rat Unigene: 321709 Human Unigene: 290884 Mouse Unigene: 463383 Mouse Unigene: 7176 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
三磷酸腺苷门控阳离子通道蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 神经生物学 信号转导 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid