乳腺癌易感基因2和p21蛋白抑制因子抗体
规格:1mg/1ml
英文名: BCCIP
别名: bccip; BCCIP_HUMAN; BCCIPalpha; BCCIPbeta; BRCA2 and CDKN1A interacting protein; BRCA2 and CDKN1A-interacting protein; BRCA2 and Cip1/p21 interacting protein; Cdk inhibitor p21 binding protein; P21 an
分子量: 36kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human BCCIP/TO
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞核
乳腺癌易感基因2和p21蛋白抑制因子抗体产品介绍:background: FunctionMay promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining. Function: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ). Subunit: Interacts with BRCA2, CDKN1A and MTDH/LYRIC. Subcellular Location: Nucleus. Note=Colocalizes with BRCA2 in乳腺癌易感基因2和p21蛋白抑制因子抗体 discrete nuclear foci. Tissue Specificity: Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen. Similarity: Belongs to the BCP1 family. Gene ID:乳腺癌易感基因2和p21蛋白抑制因子抗体 56647 Database links: Entrez Gene: 56647 Human Omim: 611883 Human SwissProt: Q9P287 Human Unigene: 370292 Human Unigene: 715543 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乳腺癌易感基因2和p21蛋白抑制因子抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞周期蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid