精氨酸酶1抗体
规格：1mg/1ml
英文名： Arginase 1
别名： liver Arginase; ARG 1; ARG1; ARGI1_HUMAN; Arginase1; Arginase liver; Arginase type I; Arginase I; ArginaseI; Arginase-1; Arginase1; Liver type arginase; Liver-type arginase; Type I arginase.
分子量： 35kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Arginase
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位：细胞浆
精氨酸酶1抗体产品介绍：background: Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence. Subunit: Homotrimer. Subcellular Location: Cytoplasm. DISEASE: Defects in ARG1 are the cause of argininemia (ARGIN) ; also known as精氨酸酶1抗体 hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia. Similarity: Belongs to the arginase family. Database links: Entrez Gene: 513608 Cow Entrez Gene: 383 Human Entrez Gene: 11846 Mouse Entrez Gene: 397115 Pig Entrez Gene: 100008814 Rabbit Entrez Gene: 29221 Rat Omim: 608313 Human SwissProt: Q2KJ64 精氨酸酶1抗体Cow SwissProt: P05089 Human SwissProt: Q61176 Mouse SwissProt: Q95JC8 Pig SwissProt: Q95KM0 Rabbit SwissProt: P07824 Rat Unigene: 440934 Human Unigene: 154144 Mouse Unigene: 9857 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
精氨酸酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid