间隙连接蛋白29/GJE1抗体
规格：1mg/1ml
英文名： Connexin 29
别名： Connexin 29; connexin29; connexin-29; Connexin 30.2; Connexin 31.3; Connexin-30.2; Connexin-31.3; CX23; Cx29 ; Cx30.2; Cx31.3; CXG3_HUMAN; Gap junction epsilon 1 protein; Gap junction epsilon-1 protei
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Connexin
交叉反应：Human, Mouse, Rat, Horse, Rabbit,
细胞定位：细胞膜
间隙连接蛋白29/GJE1抗体产品介绍：background: Connexin 29 belongs to the connexin family and is a member of the epsilon-type subfamily. Connexin 29 is a membrane bound, multi-pass protein also known as gap junction epsilon-1 protein. A connexon, consisting of connexin hexamers, is a membrane bound structure that is integral in the formation of a gap junction. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Connexin 29 expression is restricted to the central nervous system and is present in brain, spinal cord, and sciatic nerve samples. It has been suggested that connexin 29 in the mature CNS contributes minimally to gap junctional intercellular communication in oligodendrocyte cell bodies. Rather, connexin 29 is targeted to myelin where it, along with connexin 32, may contribute to connexin-mediated communication 间隙连接蛋白29/GJE1抗体between adjacent layers of uncompacted myelin. Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Subunit: A connexon is composed of a hexamer of connexins (By similarity). Subcellular Location: Cell membrane. Cell junction; gap junction. Tissue Specificity: CNS specific.间隙连接蛋白29/GJE1抗体 Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney. Similarity: Belongs to the connexin family. Gamma-type subfamily. Database links: UniProtKB/Swiss-Prot: Q8NFK1.1 Entrez Gene: 349149 Human Omim: 611925 Human SwissProt: Q8NFK1 Human Unigene: 647524 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
间隙连接蛋白29/GJE1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid