RBJ蛋白抗体
规格：1mg/1ml
英文名： RBJ
别名： DJC27_HUMAN; DKFZp434N211; DnaJ (Hsp40) homolog, subfamily C, member 27; DnaJ homolog subfamily C member 27; DNAJC27; rab and DnaJ domain containing; Rab and DnaJ domain-containing protein; RABJS; Ras
分子量： 31kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RBJ
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核
RBJ蛋白抗体产品介绍：Function: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. Subunit: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms). Subcellular Location: Nucleus. Tissue Specificity: Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers. Similarity: Belongs to the small GTPase superfamily. Rab family. RBJ蛋白抗体Contains 1 J domain. Gene ID: 51277 Database links: Entrez Gene: 402783 Chicken Entrez Gene: 540033 Cow Entrez Gene: 51277 Human Entrez Gene: 217378 Mouse Entrez Gene: 298859 Rat Entrez Gene: 402784 Zebrafish Omim: 613527 Human SwissProt: Q6IMM1 Chicken SwissProt: A5D7F5 Cow SwissProt: Q9NZQ0 Human SwissProt: Q8CFP6 Mouse SwissProt: Q6IML7 Rat SwissProt: Q6IMK3 Zebrafish Unigene: 434993 RBJ蛋白抗体Human Unigene: 271656 Mouse Unigene: 22692 Rat Unigene: 92915 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RBJ蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 结合蛋白 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid