受体表达蛋白5/息肉相关蛋白抗体
规格:1mg/1ml
英文名: REEP5
别名: C5orf18; DP1; Polyposis locus protein 1; Receptor expression enhancing protein 5; Receptor expression-enhancing protein 5; TB2; TB2 protein; D5S346;REEP5_HUMAN.
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human REEP5
交叉反应:Human, Mouse, Rat, Pig, Horse,
细胞定位:细胞膜
受体表达蛋白5/息肉相关蛋白抗体产品介绍:background: REEP5 is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the受体表达蛋白5/息肉相关蛋白抗体 TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Function: May promote functional cell surface expression of olfactory receptors. Subunit: Interacts with ATL1 (By similarity). Interacts with ATL2. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Similarity: Belongs to the DP1 family. Database links: Entrez Gene: 7905 Human Entrez Gene: 13476 受体表达蛋白5/息肉相关蛋白抗体Mouse Entrez Gene: 364838 Rat Omim: 125265 Human SwissProt: Q00765 Human SwissProt: Q60870 Mouse SwissProt: B2RZ37 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
受体表达蛋白5/息肉相关蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid