含纤维蛋白原C结构域蛋白1抗体
规格：1mg/1ml
英文名： FIBCD1
别名： FIBCD 1; Fibrinogen C domain containing 1; Fibrinogen C domain containing protein 1; FLJ14810; FBCD1_HUMAN.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FIBCD1
交叉反应：Human, Mouse, Rat, Pig, Cow, Zebrafish, Sheep,
细胞定位：细胞浆 细胞膜
含纤维蛋白原C结构域蛋白1抗体产品介绍：background: FIBCD1 is a 461 amino acid single-pass membrane protein that contains one fibrinogen C-terminal domain and exists as multiple alternatively spliced isoforms. The gene encoding FIBCD1 maps to human chromosome 9, which contains 145 million base pairs, comprises 4% of the human genome and encodes nearly 900 genes. Function: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity含纤维蛋白原C结构域蛋白1抗体 in response to elevated NAD levels during fasting. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro. Subunit: Interacts with CPS1 (By similarity). Monomer. Homodimer. Forms homodimers upon suramin binding. Subcellular Location: Mitochondrion matrix. Mitochondrion intermembrane space. Isoform 1: Cytoplasm. Mitochondrion. Isoform 2: Mitochondrion. Tissue Specificity: Widely expressed. Similarity: Belongs to 含纤维蛋白原C结构域蛋白1抗体the sirtuin family. Class III subfamily. Contains 1 deacetylase sirtuin-type domain. Database links: Entrez Gene: 84929 Human Entrez Gene: 98970 Mouse Entrez Gene: 311861 Rat SwissProt: Q8N539 Human SwissProt: A2AV25 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产含纤维蛋白原C结构域蛋白1抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid