磷酸二酯酶4B抗体
规格：1mg/1ml
英文名： PDE4B
别名： 5''-cyclic phosphodiesterase 4B; cAMP-specific 3''; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; cAMP-specific 3'5'-cyclic Phosphodiesterase 4B; cAMP-specific phosphodiesterase-4 B isoform; DKFZp6
分子量： 107kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDE4B
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
磷酸二酯酶4B抗体产品介绍：background: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] Function: 磷酸二酯酶4B抗体Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. Tissue Specificity: Expressed in brain, heart, lung and skeletal muscle. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4磷酸二酯酶4B抗体 subfamily. Gene ID: 5142 Database links: Entrez Gene: 5142 Human Entrez Gene: 18578 Mouse Entrez Gene: 24626 Rat Omim: 600127 Human SwissProt: Q07343 Human SwissProt: P14646 Rat Unigene: 198072 Human Unigene: 20181 Mouse Unigene: 37733 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸二酯酶4B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid