肌球蛋白重链9抗体
规格：1mg/1ml
英文名： MYH9
别名： Myosin heavy polypeptide 9 non muscle; Myosin-9; Myosin9; Myosin 9; Alternative namesnon-muscle IIa; type A; Cellular myosin heavy chain; Cellular myosin heavy chain type A; DFNA 17; DFNA17; EPSTS; FT
分子量： 226kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human MYH9
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：细胞浆
肌球蛋白重链9抗体产品介绍：background: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Defects in MYH9 are the cause of May-Hegglin anomaly (MHA) . MHA is an autosomal dominant macrothrombocytopenia characterized by thrombocytopenia, giant platelets and leukokyte inclusions appearing as highly parallel paracrystalline bodies. Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Subunit: Interacts with PDLIM2 (By similarity). Interacts with SLC6A4. Myosin is a hexameric protein that consists of 2 heavy chain subunits 肌球蛋白重链9抗体(MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with RASIP1. Interacts with DDR1. Interacts with SVIL and HTRA3. Subcellular Location: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Tissue Specificity: In the kidney, expressed in the glomeruli. Also expressed in leukocytes. Post-translational modifications: ISGylated. Similarity: Contains 1 IQ domain. Contains 1 肌球蛋白重链9抗体myosin head-like domain. Gene ID: 4627 Database links: Entrez Gene: 4627 Human Entrez Gene: 17886 Mouse Entrez Gene: 25745 Rat Omim: 160775 Human SwissProt: P35579 Human SwissProt: Q8VDD5 Mouse SwissProt: Q62812 Rat Unigene: 474751 Human Unigene: 29677 Mouse Unigene: 11385 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌球蛋白重链9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid