MREG蛋白抗体
规格：1mg/1ml
英文名： MREG
别名： Dilute suppressor; Dilute suppressor protein homolog; DSU; Melanoregulin; MGC90296; MREG; WDT 2; WDT2; Whn dependent transcript 2; MREG_HUMAN.
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DSU/MREG
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
MREG蛋白抗体产品介绍：background: The photoreceptor rod cell that is responsible for vision under conditions of low light consists of stacked arrays of disk membranes that make up its outer segment portion. Regulated by complex biochemical mechanisms, the rod outer segment is under constant renewal as new disks form at the base. MREG is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG interacts with RDS (also known as Peripherin-2), a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. MREG is 214 amino acids in MREG蛋白抗体length, is expressed in photoreceptor cells and and is expressed as two isoforms due to alternative splicing. Function: Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity). Subunit: Interacts with PRPH2 (By similarity). Subcellular Location: Apical cell membrane; Peripheral membrane protein. Tissue Specificity:MREG蛋白抗体 Expressed in photoreceptor cells (at protein level). Similarity: Belongs to the melanoregulin family. Database links: Entrez Gene: 55686 Human Entrez Gene: 381269 Mouse Omim: 609207 Human SwissProt: Q8N565 Human SwissProt: Q6NVG5 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MREG蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid