干扰素诱导35蛋白抗体
规格：1mg/1ml
英文名： IFI35
别名： IFI 35; Ifi-35; IFI35; IFP 35; IFP35; IN35; IN35_HUMAN; Interferon induced 35 kDa protein; Interferon-induced 35 kDa protein.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IFI35
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞核
干扰素诱导35蛋白抗体产品介绍：background: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling 干扰素诱导35蛋白抗体and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events. Function: Not yet known. Subunit: Homodimer. Also interacts with B-ATF. Subcellular Location: Nucleus. Nuclear following IFN treatment. Tissue Specificity: In a 干扰素诱导35蛋白抗体wide range of cell types, including fibroblasts, macrophages, and epithelial cells. Similarity: Belongs to the NMI family. Gene ID: 3430 Database links: Entrez Gene: 3430 Human Omim: 600735 Human SwissProt: P80217 Human Unigene: 632258 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产干扰素诱导35蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡 细胞周期蛋白 细胞分化
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid