凋亡相关蛋白11抗体
规格：1mg/1ml
英文名： PDCD11
别名： ALG 4; ALG4; apoptosis-linked gene 4; KIAA0185; NF kappa B binding protein; NFBP; PDCD 11; Programmed cell death 11; Programmed cell death protein 11; Protein RRP5 homolog.
分子量： 209kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDCD11
交叉反应：Human, Mouse,
细胞定位：细胞核
凋亡相关蛋白11抗体产品介绍：background: PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008] Function: Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA. Subunit: Interacts with凋亡相关蛋白11抗体 NF-kappa-B p50/NFKB1 and NF-kappa-B p65/RELA. Subcellular Location: Nuclear; nucleolus. Similarity: Contains 4 HAT repeats. Contains 12 S1 motif domains. Database links: Entrez Gene: 526867 Cow Entrez Gene: 22984 Human Entrez Gene:凋亡相关蛋白11抗体 18572 Mouse Omim: 612333 Human SwissProt: A7MB10 Cow SwissProt: Q14690 Human SwissProt: Q6NS46 Mouse Unigene: 239499 Human Unigene: 41166 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
凋亡相关蛋白11抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid