补体C1q和肿瘤坏死因子相关蛋白10抗体
规格：1mg/1ml
英文名： C1QTNF10
别名： C1q and tumor necrosis factor related protein 10; C1q domain containing protein; C1QL2; C1QL2_HUMAN; C1QTNF10; Complement C1q-like protein 2; Complement component 1, q subcomponent-like 2; CTRP10; gli
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from hu C1QL2/C1QTN
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：分泌型蛋白
补体C1q和肿瘤坏死因子相关蛋白10抗体产品介绍：background: C1qL2, also known as CTRP10 or C1QTNF10, is a 287 amino acid secreted protein that contains one C1q domain and one collagen-like domain. C1qL2 belongs to a large family of multimeric proteins with a signature globular domain homologous to C1QA. These proteins also share structural homology with TNF family members. The gene that encodes C1qL2 consists of approximately 2,653 bases and maps to human chromosome 2q14.2. Consisting of 237 million bases, chromosome 2 encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the补体C1q和肿瘤坏死因子相关蛋白10抗体 ALMS1 gene. Function: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Subunit: Forms homotrimers which can further assemble to form higher-order oligomeric complexes (By similarity). Interacts with BAI3 (By similarity). May interact with FAM132B (By similarity). Subcellular Location: Secreted. 补体C1q和肿瘤坏死因子相关蛋白10抗体Similarity: Contains 1 C1q domain. Contains 1 collagen-like domain. Database links: Entrez Gene: 165257 Human Entrez Gene: 226359 Mouse Omim: 614330 Human SwissProt: Q7Z5L3 Human SwissProt: Q8CFR0 Mouse Unigene: 433493 Human Unigene: 337409 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
补体C1q和肿瘤坏死因子相关蛋白10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 IEM=1:20-200 IGS=1:20-200 GICA=1:20-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid