3号染色体开放阅读框21抗体
规格：1mg/1ml
英文名： C3orf21
别名： Chromosome 3 open reading frame 21; FLJ35155; Hypothetical protein LOC152002; OTTHUMP00000208916; PSEC0251; Uncharacterized protein C3orf21; XXLT1_HUMAN.
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C3orf21/
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞浆 细胞膜
3号染色体开放阅读框21抗体产品介绍：background: C3orf21, also known as FLJ35155, is a 393 amino acid single-pass membrane protein that exists as three alternatively spliced isoforms. C3orf21 is encoded by a gene that maps to human chromosome 3q29. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a3号染色体开放阅读框21抗体 few of the numerous genetic diseases associated with chromosome 3. Function: Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of the second xylose. Subunit: Monomer. Homodimer. Dimer formation may be essential for the retention in endoplasmic reticulum. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Similarity: Belongs to the glycosyltransferase 8 family. 3号染色体开放阅读框21抗体Gene ID: 152002 Database links: Entrez Gene: 152002 Human SwissProt: Q8NBI6 Human SwissProt: Q3U4G3 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产3号染色体开放阅读框21抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 IEM=1:20-200 IGS=1:20-200 GICA=1:20-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid