纤溶酶相关蛋白B2抗体
规格：1mg/1ml
英文名： PLGLB2
别名： Plasminogen like B2; Plasminogen pseudogene 1; Plasminogen related protein B; PLGLB 2; PLGP 1; PLGP1; Type B plasminogen related.
分子量： 8.5kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PLGLB2
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：
纤溶酶相关蛋白B2抗体产品介绍：background: Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the fibrinolytic system.Plasminogen related protein B is encoded by the PLGLB1 and PLGLB2 genes. It may bind to lysine binding sites present in the kringle structures of plasminogen interfering with the binding of fibrin or alpha-2-antiplasmin to plasminogen. Within the fibrinolytic cascade, the serine proteinases urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) activate the proenzyme plasminogen by cleaving plasminogen to form the fibrinolytically active enzyme plasmin. PLGLB2 (plasminogen-like B2),纤溶酶相关蛋白B2抗体 also known as PLGP1, is a 96 amino acid protein that resembles the N-terminal plasminogen activation peptide, which is released from plasminogen during conversion to plasmin. Function: May bind noncovalently to lysine binding sites present in the kringle structures of plasminogen. This may interfere with the binding of fibrin or alpha-2-antiplasmin to plasminogen and may result in the localization of activity 纤溶酶相关蛋白B2抗体at sites necessary for extracellular matrix destruction. Similarity: Contains 1 PAN domain. Database links: Entrez Gene: 5342 Human SwissProt: Q02325 Human Unigene: 652169 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
纤溶酶相关蛋白B2抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学
储存条件： Store at -20 °c for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid