转钴胺素蛋白2抗体
规格：1mg/1ml
英文名： TCN2
别名： Macrocytic anemia; TC; TC II; TC-2; TC2; TCII; TCN 2; TCO2_HUMAN; Transcobalamin 2; Transcobalamin II; Transcobalamin II; macrocytic anemia; Transcobalamin-2; Vitamin B12 binding protein 2.
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TCN2/Tra
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：分泌型蛋白
转钴胺素蛋白2抗体产品介绍：background: Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions. Function: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. Subcellular Location: Secreted. DISEASE: Defects in TCN2 are the转钴胺素蛋白2抗体 cause of transcobalamin II deficiency (TCN2 deficiency) [MIM:275350]. This results in various forms of anemia. Similarity: Belongs to the eukaryotic cobalamin transport proteins family. Database links: Entrez Gene: 6948 Human Omim: 275350 Human SwissProt: 275350 Human SwissProt: P20062 Human Unigene: 417948 Human Important Note: This product as supplied is intended for research use 转钴胺素蛋白2抗体only, not for use in human, therapeutic or diagnostic applications. Involvement in disease;Defects in TCN2 are the cause of transcobalamin II deficiency (TCN2 deficiency) [MIM:275350]. This results in various forms of anemia.
转钴胺素蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid