胰岛素样生长因子酸不稳定亚基ALS抗体
规格：1mg/1ml
英文名： IGFALS
别名： Albs; IGFALS; Insulin like growth factor binding protein acid labile subunit; Insulin like growth factor binding protein complex acid labile chain; MGC150140; MGC150141; KIAA4111; mKIAA4111; ALS_HUMAN
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IGFALS
交叉反应：Human, Mouse, Rat,
细胞定位：细胞外基质 分泌型蛋白
胰岛素样生长因子酸不稳定亚基ALS抗体产品介绍：background: The Insulin-like growth factor binding proteins, or IGFBPs, are a family of seven proteins that have co-evolved with the IGFs. IGFBPs serve as shuttle molecules for both IGF-I and IGF-II and confer a level of regulation to the IGF signaling system by influencing the bio-availability, concentration and distribution of IGFs in the extracellular environment. In human circulation, the IGF-binging protein complex requires ALS (IGFBP acid-labile subunit), an extracellular protein involved in receptor-ligand binding and cell adhesion. ALS, detected primarily in plasma, is involved in protein-protein interactions that result in the formation of protein胰岛素样生长因子酸不稳定亚基ALS抗体 complexes. Function: Involved in protein-protein interactions that result inprotein complexes, receptor-ligand binding or cell adhesion. Subunit: Forms a ternary complex of about 140 to 150 kDa withIGF-I or IGF-II and IGFBP-3.胰岛素样生长因子酸不稳定亚基ALS抗体 Subcellular Location: Secreted; extracellular space. Tissue Specificity: Plasma. Similarity: Contains 19 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Gene ID: 3483 Database links: Entrez Gene: 3483 Human Omim: 601489 Human SwissProt: P35858 Human Unigene: 839 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胰岛素样生长因子酸不稳定亚基ALS抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid