11号染色体开放阅读框21抗体
规格:1mg/1ml
英文名: C11orf21
别名: chromosome 11 open reading frame 21; CK021_HUMAN; Uncharacterized protein C11orf21.
分子量: 14kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C11orf21
交叉反应:Human,
细胞定位:细胞浆
11号染色体开放阅读框21抗体产品介绍:background: C11orf21 is a 132 amino acid cytoplasmic protein that is expressed exclusively in heart and is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations11号染色体开放阅读框21抗体. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed exclusively in heart. Database 11号染色体开放阅读框21抗体links: UniProtKB/Swiss-Prot: Q9P2W6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
11号染色体开放阅读框21抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 **学 神经生物学 细胞周期蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid