11号染色体开放阅读框67抗体
规格:1mg/1ml
英文名: C11ORF67
别名: Chromosome 11 open reading frame 67; CK067; FLJ21035; Hypothetical protein LOC28971; MGC3367; PTD015; UPF0366 protein C11orf67; AAMDC_HUMAN.
分子量: 13kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C11ORF67
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
11号染色体开放阅读框67抗体产品介绍:background: PTD015 is a 122 amino acid protein that belongs to the UPF0366 family. Existing as three alternatively spliced isoforms, the PTD015 gene is conserved in dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 11q14.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia.11号染色体开放阅读框67抗体 The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.11号染色体开放阅读框67抗体 The PTD015 gene product has been provisionally designated PTD015 pending further characterization. Function: May play a role in preadipocyte differentiation and adipogenesis (By similarity). Subcellular Location: Cytoplasm (By similarity). Note=Diffuse distribution with some highly concentrated spots around the nucleus (By similarity). Similarity: Belongs to the AAMDC family. Database links: Entrez Gene: 28971 Human SwissProt: Q9H7C9 Human SwissProt: Q8R0P4 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产11号染色体开放阅读框67抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 细胞周期蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid