桥粒糖蛋白4抗体
规格：1mg/1ml
英文名： Desmocollin 4
别名： Cadherin family member 4; CDHF3; Desmocollin 4; Desmocollin-3; Desmocollin-4; Desmocollin3; Desmocollin4; DSC; DSC1; DSC2; DSC3; DSC3_HUMAN; DSC4; HT CP; HT-CP; HTCP.
分子量： 85kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Desmocol
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
桥粒糖蛋白4抗体产品介绍：background: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Subcellular Location: Cell membrane. Cell junction > desmosome. Tissue Specificity: Epidermis, buccal mucosa, esophagus and cervix. DISEASE: Defects in DSC3 are the cause of hypotrichosis and recurrent skin vesicles (HRSV) [MIM:613102]. A disorder characterized by hypotrichosis and the appearance of recurrent skin vesicle formation. Affected individuals show sparse and fragile hair on scalp, as well as absent eyebrows and eyelashes. Vesicles filled with thin, watery fluid are observed 桥粒糖蛋白4抗体on the scalp and skin of most of the boby. Mucosal vesicles are absent. Database links: Entrez Gene: 1825 Human Entrez Gene: 13507 Mouse Entrez Gene: 307563 Rat Omim: 600271 Human SwissProt: Q14574 Human SwissProt: P55850 Mouse Unigene: 41690 Human Unigene: 89935 Mouse Unigene: 99931 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic 桥粒糖蛋白4抗体or diagnostic applications. Involvement in disease;Defects in DSC3 are the cause of hypotrichosis and recurrent skin vesicles (HRSV). A disorder characterized by hypotrichosis and the appearance of recurrent skin vesicle formation. Affected individuals show sparse and fragile hair on scalp, as well as absent eyebrows and eyelashes. Vesicles filled with thin, watery fluid are observed on the scalp and skin of most of the boby. Mucosal vesicles are absent.
桥粒糖蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞粘附分子 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid