成簇相关蛋白1抗体
规格:1mg/1ml
英文名: CLUAP1
别名: Clusterin associated protein 1; FLJ13297; KIAA0643; CLUA1_HUMAN.
分子量: 48kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CLUAP1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep,
细胞定位:细胞核
成簇相关蛋白1抗体产品介绍:background: CLUAP1 (Clusterin associated protein 1) is a 413 amino acid nuclear protein that exists as two alternatively spliced isoforms that interact with Clusterin. CLUAP1 is suggested to play a role in apoptosis and cell proliferation, and is expressed in testis, thrachea and thyroid, with low levels found in adrenal gland and spinal cord. The gene encoding CLUAP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with 成簇相关蛋白1抗体growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: May play a role in cell proliferation or apoptosis. Subunit: Interacts with CLU/clusterin. Subcellular Location: Nuclear Tissue Specificity: Expressed in testis, thyroid and trachea and to a lower extent in spinal cord and adrenal gland. Database links: 成簇相关蛋白1抗体UniProtKB/Swiss-Prot: Q96AJ1.4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
成簇相关蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid