钙激活蛋白酶12抗体
规格：1mg/1ml
英文名： Calpain 12
别名： Calpain12; Calpain-12; CAPN 12; CAPN12; EC 3.4.22.; MGC20576; CAN12_HUMAN.
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Calpain
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：
钙激活蛋白酶12抗体产品介绍：background: Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin and cytoskeletal interactions, and synaptic plasticity. Calpain 12 was first described in the mouse, most strongly in the skin, and maps to mouse chromosome 7. Isoforms differ in the carboxyterminal ends, ending with aberrant domain III and lacking domain IV. Domains in the large subunit include the amino terminal domain I,钙激活蛋白酶12抗体 the proteinase domain II, domain III, and the EF hand domain IV, making Calpain 12 most similar to calpains 1 and 2. Function: Calcium-regulated non-lysosomal thiol-protease (By similarity). Similarity: Belongs to the peptidase C2 family. Contains 1 calpain catalytic domain. Contains 1 EF-hand domain. Gene ID: 147968 Database links: Entrez Gene: 147968 Human Entrez Gene: 60594 Mouse Entrez Gene: 钙激活蛋白酶12抗体308476 Rat Omim: 608839 Human SwissProt: Q6ZSI9 Human SwissProt: Q9ER56 Mouse Unigene: 731775 Human Unigene: 476990 Mouse Unigene: 219171 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙激活蛋白酶12抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid