酸性核磷蛋白32家族B抗体
规格：1mg/1ml
英文名： PHAPI2
别名： Acidic (leucine rich) nuclear phosphoprotein 32 family member B; Acidic leucine rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic nu
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PHAPI2/A
交叉反应：Human, Mouse, Rat, Dog, Cow, Fruit Fly, ,SheepDog,Zebrafish
细胞定位：细胞核 细胞浆
酸性核磷蛋白32家族B抗体产品介绍：background: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. Subunit: Monomer. Interacts with histones H3 and H4. Subcellular Location: Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase (By similarity). Isoform 2: Cytoplasm酸性核磷蛋白32家族B抗体. Note=Lacks a nuclear localization signal. Tissue Specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta. Post-translational modifications: Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity). Similarity: Belongs to the ANP32 family. 酸性核磷蛋白32家族B抗体Contains 4 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Gene ID: 10541 Database links: Entrez Gene: 10541 Human Entrez Gene: 67628 Mouse Entrez Gene: 170724 Rat SwissProt: Q92688 Human SwissProt: Q9EST5 Mouse SwissProt: Q9EST6 Rat Unigene: 494604 Human Unigene: 263913 Mouse Unigene: 20465 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酸性核磷蛋白32家族B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞凋亡 细胞周期蛋白 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid