锌指蛋白146抗体
规格:1mg/1ml
英文名: ZNF146
别名: Only zinc finger protein; OZF; OZF_HUMAN; Zfp146; Zinc finger protein 146; Zinc finger protein OZF; ZNF146; MGC125660; MGC125661.
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZNF146
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
锌指蛋白146抗体产品介绍:background: Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers. Subunit: Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP. Subcellular Location: Nucleus. Tissue Specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many 锌指蛋白146抗体pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers. Post-translational modifications: Sumoylated. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 10 C2H2-type zinc fingers. Gene ID: 7705 Database links: Entrez Gene: 100138954锌指蛋白146抗体 Cow Entrez Gene: 282395 Cow Entrez Gene: 7705 Human Entrez Gene: 26465 Mouse Entrez Gene: 677248 Mouse Omim: 601505 Human SwissProt: Q28151 Cow SwissProt: Q15072 Human SwissProt: Q8BQN6 Mouse Unigene: 643436 Human Unigene: 446516 Mouse Unigene: 456449 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白146抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 肿瘤细胞生物标志物 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid