纤溶酶原激活物抑制剂1 RNA结合蛋白抗体
规格:1mg/1ml
英文名: SERBP1
别名: CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI 1 mRNA binding protein; PAI RBP1; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; SERPINE1
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SERBP1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit,
细胞定位:细胞核 细胞浆
纤溶酶原激活物抑制剂1 RNA结合蛋白抗体产品介绍:background: SERBP1 (Plasminogen activator inhibitor 1 RNA-binding protein) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3’-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. SERBP1 interacts with CHD3 and is localized in cytoplasmic and nuclear. It is expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. Function: May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay纤溶酶原激活物抑制剂1 RNA结合蛋白抗体. Subunit: Interacts with CHD3 and TDRD3. Subcellular Location: Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Tissue Specificity: Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, 纤溶酶原激活物抑制剂1 RNA结合蛋白抗体liver and brain. Gene ID: 26135 Database links: Entrez Gene: 26135 Human Entrez Gene: 66870 Mouse Entrez Gene: 246303 Rat Omim: 607378 Human SwissProt: Q8NC51 Human SwissProt: Q9CY58 Mouse SwissProt: Q6AXS5 Rat Unigene: 530412 Human Unigene: 240490 Mouse Unigene: 440861 Mouse Unigene: 203108 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
纤溶酶原激活物抑制剂1 RNA结合蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导 肿瘤细胞生物标志物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid