T**瘤侵袭转移诱导蛋白1抗体
规格：1mg/1ml
英文名： TIAM1
别名： T cell lymphoma invasion and metastasis 1; T lymphoma invasion and metastasis inducing TIAM1 protein; T-lymphoma invasion and metastasis-inducing protein 1; TIAM-1; TIAM1; TIAM1_HUMAN.
分子量： 191kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TIAM1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：细胞膜
T**瘤侵袭转移诱导蛋白1抗体产品介绍：background: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Function: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Subunit: Component of the Par polarity complex, composed of at least phosphorylated PRKCZ, PARD3 and TIAM1. Interacts with NTRK2; mediates the activation of RAC1 by BDNF (By similarity).T**瘤侵袭转移诱导蛋白1抗体 Interacts with BAIAP2. Interacts with EPHA8; regulates clathrin-mediated endocytosis of EPHA8. Subcellular Location: Cell junction. Tissue Specificity: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas. Similarity: Belongs to the TIAM family. Contains 1 DH (DBL-homology) domain. Contains 1 PDZ (DHR) domain. ContainsT**瘤侵袭转移诱导蛋白1抗体 2 PH domains. Contains 1 RBD (Ras-binding) domain. Database links: UniProtKB/Swiss-Prot: Q13009.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
T**瘤侵袭转移诱导蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid