膜蛋白CLDND1抗体
规格：1mg/1ml
英文名： CLDND1
别名： C3orf4; Chromosome 3 open reading frame 4; Claudin domain containing 1; Claudin domain containing 1 protein; Membrane protein GENX3745; CLDN1_HUMAN.
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CLDND1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：细胞膜
膜蛋白CLDND1抗体产品介绍：background: CLDND1 is a 253 amino acid multi-pass membrane protein that is expressed at high levels in ***** brain and at lower levels in ***** heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Subcellular Location: Membrane;膜蛋白CLDND1抗体 Multi pass membrane protein. Tissue Specificity: Widely distributed in the ***** CNS with highest expression in the corpus callosum, caudate nucleus, cerebral cortex, medulla, putamen, spinal cord, substantia nigra and subthalamic nucleus. 膜蛋白CLDND1抗体Weak expression was detected in the ***** heart. Similarity: Belongs to the PMP-22/EMP/MP20 family. Database links: UniProtKB/Swiss-Prot: Q9NY35.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜蛋白CLDND1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞粘附分子 细胞表面分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid