酸敏感钾离子通道蛋白3抗体
规格：1mg/1ml
英文名： KCNK3
别名： cTBAK 1; Acid sensitive potassium channel protein TASK 1; Cardiac two pore background K(+) channel; K2p3.1; OAT1; potassium channel, subfamily K, member 3; rTASK; TASK 1; TBAK1; TWIK related acid sens
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNK3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,
细胞定位：细胞膜
酸敏感钾离子通道蛋白3抗体产品介绍：background: This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008]. Function: pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium 酸敏感钾离子通道蛋白3抗体concentration is low. When external potassium concentration is high, current is inward. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Tissue Specificity: Widespread expression in *****. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon. Similarity: Belongs to the two pore 酸敏感钾离子通道蛋白3抗体domain potassium channel (TC 1.A.1.8) family. Gene ID: 3777 Database links: Entrez Gene: 3777 Human Entrez Gene: 16527 Mouse Entrez Gene: 29553 Rat Omim: 603220 Human SwissProt: O14649 Human SwissProt: Q53SU2 Human SwissProt: O35111 Mouse SwissProt: O54912 Rat Unigene: 645288 Human Unigene: 439936 Mouse Unigene: 15536 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酸敏感钾离子通道蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 通道蛋白 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid