γ氨基丁酸运载蛋白1抗体
规格:1mg/1ml
英文名: GAT1/GABA Transporter 1
别名: GABATHG; GABATR; GABT 1; GABT1; GAT-1; SLC6A1; Sodium and chloride dependent GABA transporter 1; Solute carrier family 6 (neurotransmitter transporter GABA) member 1; Solute carrier family 6 member 1.
分子量: 66kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GABA Tra
交叉反应:Human, Mouse, Rat, Dog, Pig, Guinea Pig,
细胞定位:细胞浆 细胞膜
γ氨基丁酸运载蛋白1抗体产品介绍:background: GABA Transporter 1/GAT1 is a gamma-amino butyric acid (GABA) transporter. After its release from interneurons in the CNS, the major inhibitory neurotransmitter GABA is taken up by GABA transporters (GATs). The predominant neuronal GABA transporter GAT1 is localized in GABAergic axons and nerve terminals, where it is thought to influence GABAergic synaptic transmission by removing GABA from the synaptic cleft. Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Subunit: Interacts with MPP5. Subcellular Location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic tγ氨基丁酸运载蛋白1抗体erminals of interneurons. Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily. Database links: Entrez Gene: 415960 Chicken Entrez Gene: 6529 Human Entrez Gene: 232333 Mouse Entrez Gene: 79212γ氨基丁酸运载蛋白1抗体 Rat Omim: 137165 Human SwissProt: P30531 Human SwissProt: P31648 Mouse SwissProt: P23978 Rat Unigene: 443874 Human Unigene: 5260 Mouse Unigene: 10035 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产γ氨基丁酸运载蛋白1抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid