周期素依赖性激酶5激活结合蛋白C53抗体
规格：1mg/1ml
英文名： CDK5RAP3
别名： C53; CDK5 activator binding protein C53; CDK5 regulatory subunit associated protein 3; HSF 27; HSF27; IC53; Ischemic heart CDK5 activator binding protein C53; LXXLL/leucine zipper containing ARFbindin
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human CDK5RAP3
交叉反应：Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位：
周期素依赖性激酶5激活结合蛋白C53抗体产品介绍：background: Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation. Function: CDK5RAP3 may周期素依赖性激酶5激活结合蛋白C53抗体 be involved in cell proliferation through regulation of the CDK5 family by interaction with CDK5 receptor 1. Subunit: Interacts with CDK5R1. This interaction is prevented by the association between CDK5R1 and CDK5RAP3 (By similarity). Interacts with the enteric adenovirus serotype 41 fiber protein. Interacts with UFL1. Tissue Specificity: Ubiquitous. Expressed in heart, brain, placenta,周期素依赖性激酶5激活结合蛋白C53抗体 lung, liver, skeletal muscle, kidney and pancreas. Isoform 3 is expressed in kidney, liver, skeletal muscle and placenta. Post-translational modifications: Phosphorylated in vitro by CDK5 Similarity: Belongs to the CDK5RAP3 family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
周期素依赖性激酶5激活结合蛋白C53抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞周期蛋白 转录调节因子 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid