膜型基质金属蛋白酶胞质尾结合蛋白1抗体
规格:1mg/1ml
英文名: MTCBP1
别名: ADI 1; Adi1; Adi-1; ADI1 antibody; APL1; ARD; EC 1.13.; Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding p
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MTCBP1/A
交叉反应:Human, Mouse, Rat, Chicken, Horse,
细胞定位:细胞核 细胞浆 细胞膜
膜型基质金属蛋白酶胞质尾结合蛋白1抗体产品介绍:background: his gene encodes an enzyme that belongs to theaci-reductone dioxygenase family of metal-binding enzymes, whichare involved in methionine salvage. This enzyme may regulate mRNAprocessing in the nucleus, and may carry out different functionsdepending on its localization. Related pseudogenes have beendefined on chromosomes 8 and 20. Function: Catalyzes the formation of formate and2-keto-4-methylthiobutyrate (KMTB) from1,2-dihydroxy-3-keto-5-methylthiopentene膜型基质金属蛋白酶胞质尾结合蛋白1抗体 (DHK-MTPene). Alsodown-regulates cell migration mediated by MMP14. Necessary forhepatitis C virus replication in an otherwise non-permissive cellline. Subunit: Monomer (By similarity). Interacts with MMP14. Subcellular Location: Cytoplasm. Nucleus. Cell membrane;Peripheral membrane protein; Cytoplasmic side. Note=Localizes tothe plasma membrane when complexed to膜型基质金属蛋白酶胞质尾结合蛋白1抗体 MMP14. Tissue Specificity: Detected in heart, colon, lung, stomach,brain, spleen, liver, skeletal muscle and kidney. Similarity: Belongs to the acireductone dioxygenase (ARD) family. Database links: UniProtKB/Swiss-Prot: Q08554.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜型基质金属蛋白酶胞质尾结合蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 信号转导 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid