突触囊泡融合蛋白Unc18-3抗体
规格：1mg/1ml
英文名： Unc18-3
别名： Munc18c; Munc 18 3; Munc18 3; Munc 18-3; STXB3_HUMAN; Syntaxin-binding protein 3; Platelet Sec1 protein; PSP; Protein unc-18 homolog 3; Protein unc-18 homolog C; Unc-18C; STXBP 3; STXBP3; Sxtbp3.
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Unc18-3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞浆 细胞膜
突触囊泡融合蛋白Unc18-3抗体产品介绍：background: May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. Function: Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 突触囊泡融合蛋白Unc18-3抗体and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). Subunit: Interacts with DOC2B; the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion (By similarity). Interacts with STX4. Subcellular Location: Cytoplasm, cytosol. Cell membrane. Tissue Specificity:突触囊泡融合蛋白Unc18-3抗体 Megakaryocytes and platelets. Similarity: Belongs to the STXBP/unc-18/SEC1 family. Gene ID: 6814 Database links: Entrez Gene: 6814 Human Omim: 608339 Human SwissProt: O00186 Human Unigene: 530436 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触囊泡融合蛋白Unc18-3抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid