分子伴侣CESK1蛋白抗体
规格:1mg/1ml
英文名: CESK1
别名: CCT8L2; KCNMB3L; T complex protein 1; CESK1; chaperonin containing TCP1, subunit 8 (theta)-like 2; Putative T-complex protein 1 subunit theta-like 2; T complex protein 1; chaperonin containing TCP1, s
分子量: 59kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CESK1 (5
交叉反应:Human,
细胞定位:细胞浆
分子伴侣CESK1蛋白抗体产品介绍:background: CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome,分子伴侣CESK1蛋白抗体 neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias. Function: Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis 分子伴侣CESK1蛋白抗体Subcellular Location: Cytoplasm. Similarity: Belongs to the TCP-1 chaperonin family. Database links: Entrez Gene: 150160 Human SwissProt: Q96SF2 Human Unigene: 128342 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
分子伴侣CESK1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid