跨膜结构域边缘蛋白CEE抗体
规格：1mg/1ml
英文名： CEE
别名： C7orf20; CGI 20; CGI20; Conserved edge expressed protein; Conserved edge protein; Conserved edge-expressed protein; GET 4; GET4; GET4_HUMAN; Golgi to ER traffic protein 4 homolog (S. cerevisiae); Golg
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CEE (65-
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
细胞定位：细胞浆
跨膜结构域边缘蛋白CEE抗体产品介绍：background: Get4 is a 327 amino acid cytoplasmic protein that exists as two alternatively spliced isoforms. Get4 forms a multiprotein complex, known as the BAT3 complex, with UBL4A, BAT3 and ARSA. The BAT3 complex plays a role in transporting tail-anchored membrane proteins to the endoplasmic reticulum membrane. The gene encoding Get4 maps to human chromosome 7p22.3. Human chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: Component of the跨膜结构域边缘蛋白CEE抗体 BAT3 complex, a multiprotein complexinvolved in the post-translational delivery of tail-anchored (TA)membrane proteins to the endoplasmic reticulum membrane. TAmembrane proteins, also named type II transmembrane proteins,contain a single C-terminal transmembrane region. The complex actsby facilitating TA proteins capture by ASNA1/TRC40: it is recruitedto ribosomes 跨膜结构域边缘蛋白CEE抗体synthesizing membrane proteins, interacts with thetransmembrane region of newly released TA proteins, and transfersthem to ASNA1/TRC40 for targeting. Subunit: Component of the BAT3 complex, at least composed ofBAG6/BAT3, UBL4A and GET3/TRC35. Subcellular Location: Cytoplasm, cytosol. Similarity: Belongs to the GET4 family. Database links: UniProtKB/Swiss-Prot: Q7L5D6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
跨膜结构域边缘蛋白CEE抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid