锌指蛋白754抗体
规格:1mg/1ml
英文名: Zinc finger protein 754
别名: hREX-1; Reduced Expression 1 Protein; Reduced expression protein 1; Rex-1; REX1; Zfp-42; Zfp42; ZFP42_HUMAN; Zinc finger protein 42 homolog; Zinc finger protein 754; ZNF754.
分子量: 35 kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Rex1/Zin
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
锌指蛋白754抗体产品介绍:background: Involved in self-renewal property of ES cells (By similarity). May be involved in transcriptional regulation.Tissue specificity: Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines. Function: Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the 锌指蛋白754抗体TSIX promoter. Involved in ES cell self-renewal Subcellular Location: Nucleus. Tissue Specificity: Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines. Post-translational modifications:锌指蛋白754抗体 Polyubiquitinated by RNF12, leading to proteasomal degradation Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 4 C2H2-type zinc fingers. Database links: UniProtKB/Swiss-Prot: Q96MM3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产锌指蛋白754抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 干细胞 细胞表面分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid