小脑变性相关蛋白2抗体
规格：1mg/1ml
英文名： CDR2
别名： CDR 2; CDR 62; CDR2; CDR2_HUMAN; CDR62; Cerebellar degeneration related protein 2; Cerebellar degeneration related protein; Cerebellar degeneration-related protein 2; Major Yo paraneoplastic antigen;
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CDR2/PCD
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：
小脑变性相关蛋白2抗体产品介绍：background: CDR2 (cerebellar degeneration-related protein 2), also referred to as Yo or CDR62, is a 545 amino acid protein that is associated with the development of paraneoplastic cerebellar degeneration (PCD). PCD, an immune-mediated syndrome, belongs to a heterogeneous group of rare paraneoplastic neurologic disorders affecting the neurological system. PCD is characterized by subacute cerebellar ataxia and occurs mainly in patients with ovarian, uterine, fallopian tube or breast cancer. Patients with ovarian or breast cancer develop an immune response against cancer cell-expressed CDR2 and Purkinje neuron-expressed CDR2. The presence of the小脑变性相关蛋白2抗体 anti-CDR2 antibody in patients with PCD symptoms warrants an aggressive approach to diagnosis and treatment of the underlying cancer. Similarity: Belongs to the CDR2 family. Gene ID: 1039 Database links: Entrez Gene: 1039 Human Entrez Gene: 12585 Mouse Entrez Gene: 308958 Rat Omim: 117340 Human SwissProt: Q01850 Human SwissProt: P97817 Mouse Unigene: 513430 Human Unigene:小脑变性相关蛋白2抗体 1640 Mouse Unigene: 3537 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
小脑变性相关蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid