醛糖还原酶相关蛋白质抗体
规格：1mg/1ml
英文名： AKR1B10
别名： Aldose reductase like; Aldose reductase related protein; ARL 1; hARP; SI reductase; Small intestine reductase; AK1BA_HUMAN; AKR1B10; AKR1B11; AKR1B12; Aldo keto reductase family 1 member B10; aldo ket
分子量： 35kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AKR1B10
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞浆 分泌型蛋白
醛糖还原酶相关蛋白质抗体产品介绍：background: AKR1B10 is also known as aldose reductase-like-1 (ARL-1), small intestine reductase (SI reductase) or aldose reductase-related protein (ARP or hARP). AKR1B10 is found in many tissues but is predominantly expressed in small intestine, colon and adrenal gland. AKR1B10 is an efficient reductase for aliphatic and aromatic aldehydes. It plays a role in steroid metabolism as well as detoxification of aldehydes in digested food, and may be involved in the retinal-retinoic acid signaling pathway. AKR1B10 is prominently overexpressed in non-small cell lung carcinoma and adenocarcinoma. Cigarette smoking is an independent variable responsible for this overexpression. AKR1B10 may play a role regulating cell proliferation and cellular response to carbonyl stress. Function: Acts as all-trans-retinaldehyde 醛糖还原酶相关蛋白质抗体reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Subcellular Location: Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway. Tissue Specificity: Found in many tissues.醛糖还原酶相关蛋白质抗体 Highly expressed in small intestine, colon and adrenal gland. Similarity: Belongs to the aldo/keto reductase family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
醛糖还原酶相关蛋白质抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid