DNA结合抑制因子3抗体
规格：1mg/1ml
英文名： ID3
别名： 1R21; bHLHb25; Class B basic helix-loop-helix protein 25; DNA binding protein inhibitor ID 3; DNA-binding protein inhibitor ID-3; HEIR 1; HEIR1; Helix loop helix protein HEIR 1; Helix loop helix prote
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ID3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
DNA结合抑制因子3抗体产品介绍：background: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors. Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding DNA结合抑制因子3抗体of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors. Subunit: Interacts with COPS5 and COPS7A (By similarity). Homodimer, and heterodimer with other HLH proteins. Subcellular Location: Nucleus. Tissue Specificity: Expressed abundantly in lung, kidney and adrenal gland, but not in ***** brain. Similarity: Contains 1 bHLH (basic helix-loop-helix) DNA结合抑制因子3抗体domain. Database links: UniProtKB/Swiss-Prot: Q02535.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA结合抑制因子3抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 染色质和核信号 神经生物学 信号转导 干细胞 转录调节因子 **细胞 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid