肌醇单磷酸酶IMPA3抗体
规格：1mg/1ml
英文名： IMPAD1
别名： IMP 3; IMPA3; IMPase 3; Inositol monophosphatase domain containing protein 1; Myo inositol monophosphatase A3.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IMPAD1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞浆 细胞膜
肌醇单磷酸酶IMPA3抗体产品介绍：background: This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Function: May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation Subcellular Location:肌醇单磷酸酶IMPA3抗体 Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Post-translational modifications: Contains N-linked glycan resistant to endoglycosydase H. DISEASE: Defects in IMPAD1 are the cause of chondrodysplasia 肌醇单磷酸酶IMPA3抗体with joint dislocations GPAPP type (CDP-GPAPP) [MIM:614078]. A condition consisting of congenital joint dislocations, chondrodysplasia with short stature, micrognathia and cleft palate, and a distinctive face. Similarity: Belongs to the inositol monophosphatase family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌醇单磷酸酶IMPA3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid