维甲酸相关孤儿受体β抗体
规格:1mg/1ml
英文名: ROR beta
别名: bA133M9.1; NR1F2; Nuclear receptor ROR-beta; Nuclear receptor RZR beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; OTTHUMP00000021486; RAR related orphan receptor B; RAR
分子量: 53kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RORB
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位:细胞核
维甲酸相关孤儿受体β抗体产品介绍:background: ROR beta is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. Function: Orphan nuclear receptor required for normal 维甲酸相关孤儿受体β抗体postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter (By similarity). Subcellular Location: Nucleus (Probable). Similarity:维甲酸相关孤儿受体β抗体 Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. Database links: UniProtKB/Swiss-Prot: Q92753.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
维甲酸相关孤儿受体β抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 染色质和核信号 神经生物学 信号转导 细胞周期蛋白 细胞分化 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid