神经视锥蛋白样1抗体
规格:1mg/1ml
英文名: VILIP1
别名: VILIP-1; 21 kDa CABP; Hippocalcin like protein 3; HLP 3; HLP3; HPCAL 3; HPCAL3; HUVISL1; Neural visinin-like protein 1; Neural visinin-like type 1 protein; Neurocalcin alpha; NVL 1; NVL1; Nvp1; OZ1; R
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human VILIP1
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位:细胞浆
神经视锥蛋白样1抗体产品介绍:background: This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. Function: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. Tissue Specificity: Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).神经视锥蛋白样1抗体 Similarity: Belongs to the recoverin family. Contains 4 EF-hand domains. Gene ID: 7447 Database links: Entrez Gene: 396189 Chicken Entrez Gene: 282124 Cow Entrez Gene: 7447 Human Entrez Gene: 26950 Mouse Entrez Gene: 100173440 Orangutan Entrez Gene: 24877 Rat Omim: 600817 Human SwissProt: P62764 Chicken SwissProt: P62763 Cow SwissProt: Q4R5F7 Cynomolgus Monkey SwissProt: 神经视锥蛋白样1抗体P62760 Human SwissProt: P62761 Mouse SwissProt: Q5RD22 Orangutan SwissProt: P62762 Rat Unigene: 444212 Human Unigene: 27005 Mouse Unigene: 105934 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产神经视锥蛋白样1抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 结合蛋白 Alzheimer's
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid