肿瘤抑制基因LUCA15抗体
规格：1mg/1ml
英文名： LUCA15
别名： G15 antibody H37 antibody LUCA 15; LUCA15; Protein G15; RBM 5; Renal carcinoma antigen NY REN 9; RMB 5; RMB5; RNA binding motif protein 5; RNA binding protein 5; Tumor suppressor LUCA15; RBM5_HUMAN.
分子量： 92kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RBM5/LUC
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核
肿瘤抑制基因LUCA15抗体产品介绍：background: RBM5 (RNA binding motif protein 5) is a nuclear SR related RNA binding protein which specifically binds poly(G) RNA homopolymers in vitro. It modulates both apoptosis and the cell cycle, and retards tumor formation. Subunit: Component of the spliceosome A complex (also known as the prespliceosome). Appears to dissociate from the spliceosome upon formation of the spliceosome B complex (also known as the precatalytic spliceosome), in which the heterotrimeric U4/U6.U5 snRNPs are bound. Interacts with U2AF2; this interaction is direct. Also interacts with ACIN1, PRPF8, SFRS3, SNRPB, SNRPN, SNRNP70 and SNRNP200; these肿瘤抑制基因LUCA15抗体 interactions may be indirect. Subcellular Location: Nuclear. Tissue Specificity: Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines. Similarity: Belongs to the RBM5/RBM10 family. Contains 1 C2H2-type zinc finger. Contains 1 G-patch domain. Contains 1 RanBP2-type zinc finger. Contains 2 RRM (RNA recognition motif) domains. 肿瘤抑制基因LUCA15抗体Database links: UniProtKB/Swiss-Prot: P52756.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产肿瘤抑制基因LUCA15抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 染色质和核信号 信号转导 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid