成纤维细胞生长因子受体5抗体
规格：1mg/1ml
英文名： FGFR5
别名： FGF homologous factor receptor; FGF receptor like protein 1; FGFR 5; FGFR like protein; FGFR5; FGFRL1; FHFR; Fibroblast growth factor receptor 5; Fibroblast growth factor receptor like 1; FGRL1_HUMAN.
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FGFR5/FG
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：细胞膜
成纤维细胞生长因子受体5抗体产品介绍：background: FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between FGFRL1 and the other family members is its lack of a cytoplasmic tyrosine kinase domain. 成纤维细胞生长因子受体5抗体The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found. Function: UniProtKB/Swiss-Prot: Q8N441.1 FASTA Graphics Go to: LOCUS FGRL1_HUMAN 504 aa linear PRI 01-MAY-2013 DEFINITION RecName: Full=Fibroblast growth factor receptor-like 1; Short=FGF receptor-like protein 1; AltName: Full=FGF homologous factor receptor; AltName: Full=FGFR-like protein; AltName: Full=Fibroblast growth factor receptor 5; Short=FGFR-5; Flags: Precursor. Subunit: Interacts with FGF2 with a low affinity. Subcellular Location: Membrane; Single-pass成纤维细胞生长因子受体5抗体 type I membrane protein. Tissue Specificity: Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Database links: UniProtKB/Swiss-Prot: Q8N441.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
成纤维细胞生长因子受体5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid