神经母细胞瘤抑瘤蛋白1抗体
规格：1mg/1ml
英文名： NBL1
别名： DAN domain family member 1; DAN antibody DAND 1; DAND1; Differential screening selected gene aberrant in neuroblastoma; NB antibody NBL 1; Neuroblastoma candidate region suppression of tumorigenicity
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NBL1/DAN
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：分泌型蛋白
神经母细胞瘤抑瘤蛋白1抗体产品介绍：background: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways. Function: Possible candidate as 神经母细胞瘤抑瘤蛋白1抗体a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process. Subcellular Location: Secreted. Tissue Specificity: Most abundant in normal lung and meningioma. Similarity: Belongs to the DAN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Gene ID: 4681 Database links: Entrez Gene: 神经母细胞瘤抑瘤蛋白1抗体4681 Human Omim: 600613 Human SwissProt: P41271 Human Unigene: 654502 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经母细胞瘤抑瘤蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid