骨髓基质干细胞抗原1抗体
规格：1mg/1ml
英文名： BST1
别名： Cyclic ADP ribose hydrolase 2; ADP ribosyl cyclase 2; Bone marrow stromal antigen 1; Bone marrow stromal cell antigen 1; BST 1; BST1; BST-1; cADPr hydrolase 2; CD157; CD157 antigen; NAD(+) nucleosidas
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BST1/CD1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞膜
骨髓基质干细胞抗原1抗体产品介绍：background: Bone marrow stromal cell antigen 1 (BST1) is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. The BST1 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule (it synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores) and the second domain has adhesion/signalling properties. Bone marrow stromal cell antigen 1 facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The骨髓基质干细胞抗原1抗体 polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. Function: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Subunit: Homodimer. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: 骨髓基质干细胞抗原1抗体Widely expressed. Similarity: Belongs to the ADP-ribosyl cyclase family. Gene ID: 683 Database links: Entrez Gene: 683 Human Omim: 600387 Human SwissProt: Q10588 Human Unigene: 720344 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骨髓基质干细胞抗原1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 干细胞 b-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid